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Personalized Skincare Nutrition Based on Your Genes
Skin Nutrition: Skin Damage Due to Nutritional Deficiencies
Nutritional status plays an important role in the maintenance of healthy skin. Macronutrients (carbohydrate, protein and lipids) and micronutrients
(vitamins and minerals) work together to maintain the barrier functions of skin in the face of everyday challenges.
What role Vitamins & Minerals plays for a Healthy Skin?
Vitamins and minerals are known to play an integral role in the skin health and complexion. Similarly, new research has shown the importance of vitamin and minerals in general health and specifically their critical role in the way the skin looks, feels and how fast it ages.
A balance diet in combination with appropriate antioxidants and vitamin supplementation can help maintain health and slow down the appearance of signs of aging skin.
Vitamin a & Skin Health
Skin is a major retinoid-responsive tissue. Cells in both the epidermis and dermis contain proteins and receptors that mediate the biological effects of vitamin A metbolites in the skin. Deficiency in vitamin A is associated with various skin conditions, including dry skin, abnormal thickening of the skin, atopic dermatitis and delayed wound healing.
How Genetic variation impacts mode of Vitamin a in your skin?
Vitamin A is converted from beta-carotene in the body. Two genetic variants in the BCMO1 gene have been associated with decreased ability to convert beta-carotene to vitamin A in women (Leung WC et al).
Our SkinLife test would help you to identify if you are genetically predisposed or at risk of being retinol deficient.
Also our skin expert would provide you with recommendations on how to plan your diet and meet the expected RDA (recommended dietary allowance) for healthy skin, along with topical supplements recommendations as per your genotype report.
Vitamin C & skin Health
The antioxidant attributes of scorbic Acid (Vitamin C) and its key role in collagen synthesis makes vitamin C as a vital molecule for skin health. There are many forms of vitamin C for skin, and while they all have antioxidant benefits, some types of vitamin C work better in skin care formulas than others.
Ascorbic acid; also known as L-ascorbic acid has the most skin-related research of any form of vitamin C. When properly formulated at a pH of less than 4 (2.6-3.2 is the ideal range), this form helps create younger-looking, firmer-feeling skin while fading signs of uneven skin tone and spots.
Ascorbic acid also helps skin’s surface defend itself from free radicals and external stress, lessening the effects of exposure to the elements.
How genetic variation impacts mode of Vitamin C in your skin?
It is well established that vitamin c deficiency leads to scurvy. Skin conditions associated with scurvy includes abnormal thickening of the outer layer of skin, inflammation, delayed wound healing and dry, rough skin (all associated with collagen damage). In recent years multiple scientific studies reported a genetic variant in the SLC23A1 gene, which is associated with decreased levels of circulating vitamin C which in result have lead to several skin disorders.
Our SkinLife DNA test helps you identify your genetic predisposition or susceptibility towards being Ascorbic acid deficient. Our skin expert would provide you recommendations to plan your diet and meet the expected RDA (recommended dietary allowance) of vitamin c to maintain healthy skin along with topical supplements recommendation as per your genotype report.
How genetic variation impacts mode of folate in your skin?
As recent scientific studies have suggested that genetic variants in one or more risk alleles in the MTHFR gene are associated with individuals presenting low plasma folate levels. In addition, these variants have also been associated with varicose vein disorder.
SkinLife DNA test helps to identify your genetic susceptibility towards being Folate deficient. Our skin expert would provide you recommendations to plan your diet and meet the expected RDA (recommended dietary allowance) of folate to maintain healthy skin, along with topical supplements recommendation as per your genotype report.
Minerals associated with skin care
Folate-folic acid deficiency
Folate (folic acid) works symbiotically with vitamins B6 and B12 in DNA synthesis and amino acid metabolism. Deficiency in folate can increase the risk of skin conditions, including psoriasis, deep venous thrombosis, oral atrophy and skin aging. Individuals with these conditions may benefit from increase uptake of folate rich foods or folic acid supplementation.
Folate & Skin Health
Over secretion level of homocysteine, is considered as signature of folate deficiency, i.e associated with skin aging caused by collagen, fibrillin and elastin degradation in the skin. Folic acid helps in enhancing the firmness of the human skin and also helps reduce the signs of skin aging. Both dietary and genetic factors can influence folate levels in the body. Folate is obtained from food or synthetically as folic acid supplement.
Omega 3 fatty deficiency
Omega-6 and omega-3 polyunsaturated fatty acids (PUFAs) play a critical role in normal skin function and appearance. Metabolism of the essential fatty acids (EFAs), linoleic acid (LA) and α-linolenic acid (ALA), is limited in the skin. Long-chain derivatives of LA and ALA are therefore considered conditionally essential nutrients for skin. Deficiencies in these fatty acids can lead to various skin problems, including dermatitis, acne, scaling, dry skin, and psoriasis. Omega-6 PUFAs have a particular role in structural integrity and barrier function of the skin.
Genetic impact of omega 3 in skin health
Recent scientific studies have provided information that genetic variant in the FADS1 gene has been associated with decreased blood levels of omega-3 and omega-6. In another studies FADS1 gene variation was associated with Atopic Dermatitis condition.
Our SkinLife Omega 3 fatty acid test would identify if you need appropriate Omega 3 consumption for a healthy epidermal layer. Our skin expert would provide you recommendations to plan your diet and meet the expected RDA (recommended dietary allowance) of omega 3 to maintain healthy skin, along with topical supplements recommendation as per your genotype report.
